- Stroke risk is 5-fold with Atrial fibrillation 
 
                        - The LAAO Implant is an innovative one-time procedure designed to reduce the risk of strokes that originate in the left atrial appendage (LAA)
 
                        - Criteria: CHADS2-VASC >3
 
                        - Patient with elevated HAS-BLED score: High risk of 10-year re-bleeding
 
                        - B/w 30-50% eligible patients with Atrial fibrillation still not on AC 
 
                        - LAAO high success rate and low complication rate
 
                        - Stroke prevention is comparable to Oral AC 
 
                    
                    Potential candidates: 
                    History of bleeding
                    Increased bleeding risk based on HAS-BLED score or other factors (e.g. thrombocytopenia, cancer, or risk of tumor associated bleeding in case of systemic anticoagulation)
                    History or risk of falls 
                    Documented poor compliance with OAC therapy 
                    Inability or difficulty maintaining therapeutic range
                    Occupation that puts patient at an increased bleeding risk
                    Lifestyle or hobby that puts patient at an increased bleeding risk 
                    Severe renal failure – medical condition for which OAC inappropriate